Functional dyspepsia: from human to dog, a retrospective study of 29 cases illustrating a complex entity
Functional dyspepsia is a clinically emerging functional gastrointestinal disorder in dogs, especially in toy and small breed, middle-aged, female dogs, characterized by chronic gastrointestinal discomfort and vomiting in the absence of confirmed organic disease. The clinical picture of intense abdominal crisis with highly involved and anxious owners is out of step with the results of investigations. Overlap with food-responsive enteropathies, immunosuppressant-responsive enteropathies, or gastroduodenal dysmotility disorders is still of concern, potentially triggered by emotional disorders. Canine FD could reflect a gut-brain axis disturbance and should be included in the differential diagnosis of refractory canine upper digestive disorders. Tailored therapeutic approaches, including dietary modifications, antacids, and prokinetic agents, may offer clinical benefit.
Authors
- Hugo Kaufmann (ORCID: https://orcid.org/0000-0002-4134-151X)
- Valérie Freiche (ORCID: https://orcid.org/0000-0003-2041-078X)
- Henri Duboc (ORCID: https://orcid.org/0000-0003-4359-7129)
Institutions
- Inserm (FR)
- École Nationale Vétérinaire d'Alfort (FR)
- Université Paris Cité (FR)
- Sorbonne Paris Cité (FR)
- Centre Hospitalier Vétérinaire Frégis (FR)
- Institut des Maladies Génétiques Imagine (FR)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2025-10-10
- DOI
- https://doi.org/10.1186/s12917-025-05038-7
- Primary Topic
- Gastrointestinal motility and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00