Early-onset Sulzberger-Garbe dermatosis: a rare pediatric case report

A 14-year-old patient with a long-standing history of seasonal, recurrent eczematous eruptions since infancy was referred to our dermatology clinic due to progression of skin lesions and intense pruritus. Physical examination revealed erythematous, infiltrated plaques with erosions and post-inflammatory dyspigmentation, predominantly on the extensor surfaces of the limbs. The trunk and face were unaffected. Laboratory testing revealed mild relative eosinophilia (5.6%) in the complete blood count. Other routine tests were within normal limits. Histopathological examination of a biopsy specimen from the upper limb revealed features of acute eczema corresponding to Sulzberger-Garbe dermatosis. This case highlights a rare pediatric manifestation of Sulzberger-Garbe dermatosis. Although classically described in adult males, the condition should also be considered in adolescents with chronic, pruritic dermatoses unresponsive to conventional treatment. Comprehensive differential diagnosis - including allergy screening and histopathologic evaluation - is essential to exclude other dermatoses that share similar clinical features.

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Publication Details

Journal
Folia Medica Cracoviensia
Published
2025-10-10
DOI
https://doi.org/10.24425/fmc.2024.153281
Primary Topic
Eosinophilic Disorders and Syndromes
Type
article
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article

Early-onset Sulzberger-Garbe dermatosis: a rare pediatric case report

Magdalena Jaworek, Przemysław Hałubiec, Anna Wojas‐Pelc, Andrzej Jaworek
Folia Medica Cracoviensia
Eosinophilic Disorders and Syndromes
article

Early-onset Sulzberger-Garbe dermatosis: a rare pediatric case report

Magdalena Jaworek, Przemysław Hałubiec, Anna Wojas‐Pelc, Andrzej Jaworek
article en

Abstract

A 14-year-old patient with a long-standing history of seasonal, recurrent eczematous eruptions since infancy was referred to our dermatology clinic due to progression of skin lesions and intense pruritus. Physical examination revealed erythematous, infiltrated plaques with erosions and post-inflammatory dyspigmentation, predominantly on the extensor surfaces of the limbs. The trunk and face were unaffected. Laboratory testing revealed mild relative eosinophilia (5.6%) in the complete blood count. Other routine tests were within normal limits. Histopathological examination of a biopsy specimen from the upper limb revealed features of acute eczema corresponding to Sulzberger-Garbe dermatosis. This case highlights a rare pediatric manifestation of Sulzberger-Garbe dermatosis. Although classically described in adult males, the condition should also be considered in adolescents with chronic, pruritic dermatoses unresponsive to conventional treatment. Comprehensive differential diagnosis - including allergy screening and histopathologic evaluation - is essential to exclude other dermatoses that share similar clinical features.

Folia Medica CracoviensiaVol. 65(1)
Jagiellonian University (PL)
Openalex Percentile: Top 59%
Eosinophilic Disorders and Syndromes
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Early-onset Sulzberger-Garbe dermatosis: a rare pediatric case report — Magdalena Jaworek, Przemysław Hałubiec, et al. · Folia Medica Cracoviensia (2025) | TGRS Research Map | TGRS