Hypothermic oxygenated perfusion: cellular mechanisms and clinical outcomes
HOPE represents a significant advancement in liver transplantation, offering a safer, more efficient alternative to traditional preservation methods. By improving both clinical outcomes and being cost efficient, this technique has the potential to become a standard of care in liver transplantation. Further research should focus on refining viability assessment protocols, optimizing logistical implementation, and expanding clinical adoption to maximize organ utilization and improve patient survival.
Authors
- Chunbao Jiao (ORCID: https://orcid.org/0000-0002-9566-8243)
- Keyue Sun (ORCID: https://orcid.org/0000-0002-8928-4630)
- Chase J. Wehrle (ORCID: https://orcid.org/0000-0002-9275-4744)
- O Karakaya (ORCID: https://orcid.org/0009-0000-4950-139X)
- Andrea Schlegel
- Sangeeta Satish
- Fernanda Walsh Fernandes (ORCID: https://orcid.org/0000-0003-1260-7005)
- Fatma Selin Yildirim
- G. Crasta
Institutions
- Cleveland Clinic (US)
- Monterey Bay Aquarium Foundation (US)
Publication Details
- Journal
- Current Opinion in Organ Transplantation
- Published
- 2025-10-03
- DOI
- https://doi.org/10.1097/mot.0000000000001250
- Citations
- 1
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.01