Operational determinants of recruitment and biospecimen collection in translational observational studies: a multi-site comparative analysis
Dedicated administrative and clinical trial personnel significantly may enhance study efficiency, participant recruitment, and biospecimen collection in academic translational research. This study provides practical insights for improving study design and infrastructure planning in future observational studies. To our knowledge, this is the first multi-site comparative evaluation of operational determinants in academic MWAS.
Authors
- Bryan T. Hennessy (ORCID: https://orcid.org/0000-0002-7871-6477)
- Roisín M. Connolly (ORCID: https://orcid.org/0000-0003-0056-1070)
- Rachel Clarke (ORCID: https://orcid.org/0000-0001-9606-2510)
- Ciarán Devoy (ORCID: https://orcid.org/0000-0002-3916-2387)
- Brian Bird (ORCID: https://orcid.org/0000-0001-8562-0564)
- Erin K. Crowley (ORCID: https://orcid.org/0000-0002-0687-2665)
- Christopher Cronin (ORCID: https://orcid.org/0000-0002-2715-7273)
- Mark Tangney (ORCID: https://orcid.org/0000-0002-6314-1260)
- Dearbhaile Catherine Collins (ORCID: https://orcid.org/0000-0002-5156-0142)
- Ronan Andrew McLaughlin
- Laia Raigal
Institutions
- Royal College of Surgeons in Ireland (IE)
- University College Cork (IE)
- Bon Secours Hospital Cork (IE)
- Cork University Hospital (IE)
- APC Microbiome Institute (IE)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-10-10
- DOI
- https://doi.org/10.1186/s12967-025-07074-1
- Primary Topic
- Ethics in Clinical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Breakthrough Cancer Research