Extended window of relapse recovery in RRMS: an analysis of the DECIDE dataset

Most relapses (94.2%) recover, but the process of recovery can take up to 1 year and depends mostly on relapse severity. Our findings challenge the concept of 3-month and 6-month confirmed disability progression as reliable markers of permanent disability in RRMS trials. ACES occurs frequently and is associated with age.

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Publication Details

Journal
Journal of Neurology Neurosurgery & Psychiatry
Published
2025-10-09
DOI
https://doi.org/10.1136/jnnp-2025-336660
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
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article

Extended window of relapse recovery in RRMS: an analysis of the DECIDE dataset

Jop Mostert, Marcus Koch, Pavle Repovic, Eva M. M. Strijbis et al.
Journal of Neurology Neurosurgery & Psychiatry
Multiple Sclerosis Research Studies
article

Extended window of relapse recovery in RRMS: an analysis of the DECIDE dataset

Jop Mostert, Marcus Koch, Pavle Repovic, Eva M. M. Strijbis, Gary Cutter, James D. Bowen, Miguel D’haeseleer, Jacynthe Comtois, Luís Brieva, Ester Moral
article en

Abstract

Most relapses (94.2%) recover, but the process of recovery can take up to 1 year and depends mostly on relapse severity. Our findings challenge the concept of 3-month and 6-month confirmed disability progression as reliable markers of permanent disability in RRMS trials. ACES occurs frequently and is associated with age.

Journal of Neurology Neurosurgery & PsychiatryVol. 97(3)
Alabama Department of Public Health (US), University of Calgary (CA), Hospital Universitari Arnau de Vilanova (ES), Hôpital Maisonneuve-Rosemont (CA), Swedish Medical Center (US), Amsterdam Neuroscience (NL), Universitair Ziekenhuis Brussel (BE), Hospital de Sant Joan Despí Moisès Broggi (ES), Rijnstate Hospital (NL), Université de Montréal (CA)
Openalex Percentile: Top 60%
Multiple Sclerosis Research Studies
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