Genome‐wide scan reveals <scp>CYP450</scp> metabolism and stress response regulation underlying sulfosulfuron resistance in <scp> <i>Bromus tectorum</i> </scp>

Non-target site resistance for sulfosulfuron is present in B. tectorum populations of the inland PNW. A heat shock-related protein 70 regulator and an auxin response factor gene was near the SNP that explained 48% of the variation in the GWAS, indicating auxin regulation and stress response pathways are involved in the resistance of B. tectorum populations to sulfosulfuron. The heat shock-factor protein 70 regulated by the heat shock-related protein 70 regulator was found on another significant SNP and the SNPs those two genes were on have a significant interaction. Additionally, the GWAS analysis indicated CYP450 genes are likely involved in resistance. © 2025 Society of Chemical Industry.

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Publication Details

Journal
Pest Management Science
Published
2025-10-10
DOI
https://doi.org/10.1002/ps.70300
Primary Topic
Weed Control and Herbicide Applications
Type
article
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article

Genome‐wide scan reveals CYP450 metabolism and stress response regulation underlying sulfosulfuron resistance in Bromus tectorum

Samuel Revolinski, Marija Savic, Marcelo Nogueira do Amaral, Ian C. Burke
Pest Management Science
Weed Control and Herbicide Applications
article

Genome‐wide scan reveals CYP450 metabolism and stress response regulation underlying sulfosulfuron resistance in Bromus tectorum

Samuel Revolinski, Marija Savic, Marcelo Nogueira do Amaral, Ian C. Burke
article en

Abstract

Non-target site resistance for sulfosulfuron is present in B. tectorum populations of the inland PNW. A heat shock-related protein 70 regulator and an auxin response factor gene was near the SNP that explained 48% of the variation in the GWAS, indicating auxin regulation and stress response pathways are involved in the resistance of B. tectorum populations to sulfosulfuron. The heat shock-factor protein 70 regulated by the heat shock-related protein 70 regulator was found on another significant SNP and the SNPs those two genes were on have a significant interaction. Additionally, the GWAS analysis indicated CYP450 genes are likely involved in resistance. © 2025 Society of Chemical Industry.

Pest Management ScienceVol. 82(2)
University of Kentucky (US), Washington State University (US)
Openalex Percentile: Top 79%
Weed Control and Herbicide Applications
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