Development and validation of a leukemia prognostic model through single-cell RNA sequencing and machine learning approaches
This study provides a reliable prognostic tool for leukemia and offers insights into the critical role of the immune microenvironment in leukemia pathogenesis. Our findings may guide the development of personalized immunotherapy strategies for leukemia patients.
Authors
- Tianye Jian
- Dunjin Chen (ORCID: https://orcid.org/0000-0002-1839-3469)
- Jie Yang (ORCID: https://orcid.org/0009-0004-5820-9779)
- Mengting Wang (ORCID: https://orcid.org/0009-0007-8417-2879)
Institutions
- Zunyi Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-10-10
- DOI
- https://doi.org/10.1007/s12672-025-03757-9
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00