Clinical characteristics of children with idiopathic nephrotic syndrome infected with SARS-CoV-2: a single-center retrospective cohort study

SARS-CoV-2 infections in children with INS were mainly intrafamilial, and mostly mild. SARS-CoV-2 infection was associated with relapse in INS, and may lead to complications such as myocardial enzyme elevations, AKI, deterioration of kidney function, while upregulated steroid therapy might be effective in relapse cases of children with SSNS. Further, we found that healthy children are at risk of new-onset INS following SARS-CoV-2 infection.

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Publication Details

Journal
BMC Pediatrics
Published
2025-10-10
DOI
https://doi.org/10.1186/s12887-025-06182-7
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
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article

Clinical characteristics of children with idiopathic nephrotic syndrome infected with SARS-CoV-2: a single-center retrospective cohort study

Junyu Wei, Zihui Lin, Lyndia C. Wu, Hongchao Li et al.
BMC Pediatrics
Renal Diseases and Glomerulopathies
article

Clinical characteristics of children with idiopathic nephrotic syndrome infected with SARS-CoV-2: a single-center retrospective cohort study

Junyu Wei, Zihui Lin, Lyndia C. Wu, Hongchao Li, Chunlin Huang
article en

Abstract

SARS-CoV-2 infections in children with INS were mainly intrafamilial, and mostly mild. SARS-CoV-2 infection was associated with relapse in INS, and may lead to complications such as myocardial enzyme elevations, AKI, deterioration of kidney function, while upregulated steroid therapy might be effective in relapse cases of children with SSNS. Further, we found that healthy children are at risk of new-onset INS following SARS-CoV-2 infection.

BMC PediatricsVol. 25(1)
Guangxi Maternal and Child Health Hospital (CN)
Openalex Percentile: Top 70%
Renal Diseases and Glomerulopathies
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