Emergence of ST23-K1 blaKPC-3-positive hypervirulent carbapenem-resistant Klebsiella pneumoniae from China: A molecular, biological, and epidemiological study
The present study corroborates the emergence of hypervirulent CR-hvKP in the Zhejiang region, a phenomenon that is presumably attributable to the acquisition of an IncFIB virulence plasmid and a bla<sub>KPC-3</sub> resistance plasmid by the ST23-K1 type K. pneumoniae. Our findings highlight the urgent need to use antibiotics more wisely to limit the emergence of resistance.
Authors
- Hongwei Zhou (ORCID: https://orcid.org/0000-0002-9478-4023)
- Ling Xin (ORCID: https://orcid.org/0000-0002-1128-1667)
- Gongxiang Chen
- Jing Wang (ORCID: https://orcid.org/0000-0002-0923-8977)
- Rong Zhang (ORCID: https://orcid.org/0000-0002-4614-7644)
- Yi Sun (ORCID: https://orcid.org/0000-0002-8924-7872)
- Cong Qing
Institutions
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-10-10
- DOI
- https://doi.org/10.1016/j.jgar.2025.09.007
- Citations
- 1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.59