Design, synthesis, and synergistic activities of 2-aminothiazolyl compounds as potent colistin adjuvants against <i>Acinetobacter baumannii</i>
Novel benzothiazole C17 , a colistin adjuvant, exhibits potent synergy (FICI = 0.094) against A. baumannii and demonstrates promising in vivo efficacy.
Authors
- Xiaoyong Xu
- Zhonghui Li (ORCID: https://orcid.org/0000-0002-7835-498X)
- Yuce Chen (ORCID: https://orcid.org/0000-0003-3550-5220)
- Daijie Chen
- Lin Ting (ORCID: https://orcid.org/0000-0002-0915-3519)
- Kunkun Shen
Institutions
- East China University of Science and Technology (CN)
- Shanghai Jiao Tong University (CN)
Publication Details
- Journal
- New Journal of Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5nj03041b
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.00