Meningococcal Purpura Fulminans: A Rare Presentation in an Adult Case of Serogroup W135 Infection

Meningococcal purpura fulminans is a rare but serious complication of invasive <i>Neisseria meningitidis</i> infection, marked by widespread clotting problems and skin tissue death. Diagnosis can be tricky, especially when patients show unusual early symptoms that do not fit the classic pattern. We present an adult case infected with serogroup W135 who initially had non-specific symptoms such as sore throat, which progressed quickly to severe septic shock and purpura fulminans. The patient required intensive care and tailored treatments, including antibiotics and supportive care. This case highlights how varied the presentation can be and stresses the need for early recognition and aggressive management to improve outcomes and prevent lasting damage.

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Publication Details

Journal
Cureus
Published
2025-10-09
DOI
https://doi.org/10.7759/cureus.94253
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
0.00
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article

Meningococcal Purpura Fulminans: A Rare Presentation in an Adult Case of Serogroup W135 Infection

Mohamed Mohamedali, Hatem Abusriwil, M. I. Abd El‐Aziz, Abdulrahman Saad et al.
Cureus
Bacterial Infections and Vaccines
article

Meningococcal Purpura Fulminans: A Rare Presentation in an Adult Case of Serogroup W135 Infection

Mohamed Mohamedali, Hatem Abusriwil, M. I. Abd El‐Aziz, Abdulrahman Saad, Abdulqadir J. J. Nashwan, Usamah Al‐Anbagi, Muayad K Ahmad
article en

Abstract

Meningococcal purpura fulminans is a rare but serious complication of invasive <i>Neisseria meningitidis</i> infection, marked by widespread clotting problems and skin tissue death. Diagnosis can be tricky, especially when patients show unusual early symptoms that do not fit the classic pattern. We present an adult case infected with serogroup W135 who initially had non-specific symptoms such as sore throat, which progressed quickly to severe septic shock and purpura fulminans. The patient required intensive care and tailored treatments, including antibiotics and supportive care. This case highlights how varied the presentation can be and stresses the need for early recognition and aggressive management to improve outcomes and prevent lasting damage.

CureusVol. 17(10)
Ministry of Public Health (QA), Hamad General Hospital (QA), Hamad Medical Corporation (QA)
Openalex Percentile: Top 74%
Bacterial Infections and Vaccines
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Meningococcal Purpura Fulminans: A Rare Presentation in an Adult Case of Serogroup W135 Infection — Mohamed Mohamedali, Hatem Abusriwil, et al. · Cureus (2025) | TGRS Research Map | TGRS