Polyunsaturated Fatty Acids and Skin Cancer: Two-Sample Mendelian Randomization Study
This MR analysis supports a causal role of circulating PUFAs in skin cancer development and highlights the importance of FADS-mediated endogenous PUFA metabolism. These findings provide novel insights into the genetic and metabolic underpinnings of skin cancer susceptibility.
Authors
- Woojae Myung (ORCID: https://orcid.org/0000-0001-9985-2032)
- Seon‐Pil Jin (ORCID: https://orcid.org/0000-0002-8290-4278)
- Bo Ri Kim (ORCID: https://orcid.org/0000-0002-2223-1606)
- Hyunsun Park (ORCID: https://orcid.org/0000-0003-1338-654X)
- G. Kim
- Chong Won Choi (ORCID: https://orcid.org/0000-0001-9994-8819)
- Jin‐Ku Lee (ORCID: https://orcid.org/0000-0003-0263-3234)
- Kyungho Paik (ORCID: https://orcid.org/0000-0002-5706-2371)
- Jin-Ho Kim (ORCID: https://orcid.org/0000-0001-9524-9981)
Institutions
- Seoul National University (KR)
- New Generation University College (ET)
- Seoul National University Hospital (KR)
- Seoul National University Bundang Hospital (KR)
Publication Details
- Journal
- Annals of Dermatology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5021/ad.25.095
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Seoul National University Bundang Hospital
- Seoul National University
- Korea Health Industry Development Institute