In vivo functional screening on innate immunity of lactic acid bacteria in Galleria mellonella preclinical model: comparative analysis of Lactiplantibacillus plantarum and Lentilactobacillus kefiri
These findings suggest that <i>G. mellonella</i> could serve as a cost-effective <i>in vivo</i> model for functional screening of <i>Lactobacillus</i> spp. with immunomodulatory potential and possible translational relevance to human innate immunity.
Authors
- Sonia Ganassi (ORCID: https://orcid.org/0000-0003-2518-7628)
- Farwa Mukhtar
- Giulio Petronio Petronio (ORCID: https://orcid.org/0000-0002-5098-7785)
- Marco Alfio Cutuli (ORCID: https://orcid.org/0000-0003-1753-2399)
- Antonio Guarnieri (ORCID: https://orcid.org/0000-0003-3949-4143)
- Roberto Di Marco (ORCID: https://orcid.org/0000-0001-5075-4597)
- Antonio De Cristofaro (ORCID: https://orcid.org/0000-0002-3207-9329)
- Natasha Brancazio
- Alemayehu Worku (ORCID: https://orcid.org/0000-0002-7332-5688)
- Marilina Falcone
- Vincenzo Pio Iacovino
Institutions
- University of Molise (IT)
- University of Catania (IT)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-10-10
- DOI
- https://doi.org/10.3389/fcimb.2025.1681687
- Citations
- 1
- Primary Topic
- Invertebrate Immune Response Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.80