Neoadjuvant chemotherapy impacts axillary lymph node positivity in early breast cancer (cT1-2N0M0) with negative axillary lymph nodes at diagnosis
NAC may reduce the rate of axillary LN positivity and the likelihood of ALND in patients aged 40-60 years with cT2N0M0 HER2+ breast cancer and clinically negative axillary LNs at diagnosis.
Authors
- Zhifang Jia (ORCID: https://orcid.org/0000-0001-9838-1726)
- Zhimin Fan (ORCID: https://orcid.org/0000-0001-5236-7814)
- Jinxiu Ma
- Xiaozhen Wang (ORCID: https://orcid.org/0000-0003-0088-3221)
- Jian Sun (ORCID: https://orcid.org/0000-0003-1569-0334)
- Xiaoxiao Dong (ORCID: https://orcid.org/0009-0000-0703-253X)
Institutions
- Jilin University (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-10-10
- DOI
- https://doi.org/10.3389/fmed.2025.1672369
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- People's Government of Jilin Province
- Education Department of Jilin Province
- Wu Jieping Medical Foundation