When AI speaks like a specialist: ChatGPT-4 in the management of inflammatory bowel disease
ChatGPT-4 generated high-quality, clear, and actionable responses to IBD-related patient questions, often outperforming human experts. Its outputs were frequently indistinguishable from those written by physicians, suggesting potential as a supportive tool for patient education. Nonetheless, further studies are needed to assess real-world application and ensure appropriate use in personalized clinical care.
Authors
- Mathieu Pioche (ORCID: https://orcid.org/0000-0002-6482-2375)
- Elena De Cristofaro (ORCID: https://orcid.org/0000-0003-2818-916X)
- Emma Calabrese (ORCID: https://orcid.org/0009-0003-4635-4154)
- Gionata Fiorino (ORCID: https://orcid.org/0000-0001-5623-2968)
- Omero Alessandro Paoluzi (ORCID: https://orcid.org/0000-0002-5393-5796)
- Nurulamin M Noor (ORCID: https://orcid.org/0000-0003-3426-6408)
- G. Del Vecchio Blanco (ORCID: https://orcid.org/0000-0002-6327-563X)
- Elisabetta Lolli (ORCID: https://orcid.org/0000-0003-1267-542X)
- Joana Roseira (ORCID: https://orcid.org/0000-0002-5098-8729)
- Loris Riccardo Lopetuso (ORCID: https://orcid.org/0000-0002-5747-2055)
- Jean Grimaldi (ORCID: https://orcid.org/0009-0007-0245-2456)
- Francesca Zorzi
- Edoardo Troncone (ORCID: https://orcid.org/0000-0003-4520-6865)
- G Monteleone (ORCID: https://orcid.org/0000-0002-1469-2138)
- Irene Marafini (ORCID: https://orcid.org/0000-0001-8258-3235)
- Maria Abreu
- Giorgia Sena
- Alice Colella
Institutions
- University of Rome Tor Vergata (IT)
- University of Miami (US)
- University of Cambridge (GB)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- Agostino Gemelli University Polyclinic (IT)
- Hospices Civils de Lyon (FR)
- Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
- Centro Clinico Nemo (IT)
- Algarve Biomedical Center (PT)
- Hôpital Edouard Herriot (FR)
- Policlinico Tor Vergata (IT)
- Carlo Forlanini Hospital (IT)
Publication Details
- Journal
- Frontiers in Artificial Intelligence
- Published
- 2025-10-10
- DOI
- https://doi.org/10.3389/frai.2025.1678320
- Primary Topic
- Artificial Intelligence in Healthcare and Education
- Type
- article
- Field-Weighted Citation Impact
- 0.00