Case Report: Therapeutic biopsy guided targeted therapy improves visual acuity and prolongs survival in bilateral uveal metastases as the initial presentation of lung adenocarcinoma

This case underscores that bilateral uveal metastasis, even with ciliary body involvement, can achieve exceptional survival and visual recovery through targeted therapy. This case suggests ocular biopsy and early molecular testing may refine management for similar patients. The unexpected treatment response warrants further studies on tumor-ocular microenvironment interactions.

Authors

Institutions

Publication Details

Journal
Frontiers in Medicine
Published
2025-10-10
DOI
https://doi.org/10.3389/fmed.2025.1643966
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Case Report: Therapeutic biopsy guided targeted therapy improves visual acuity and prolongs survival in bilateral uveal metastases as the initial presentation of lung adenocarcinoma

Tongwen Ou, Chengda Ren, Yiliu Yang, Fang Lu
Frontiers in Medicine
Ocular Oncology and Treatments
article

Case Report: Therapeutic biopsy guided targeted therapy improves visual acuity and prolongs survival in bilateral uveal metastases as the initial presentation of lung adenocarcinoma

Tongwen Ou, Chengda Ren, Yiliu Yang, Fang Lu
article en

Abstract

This case underscores that bilateral uveal metastasis, even with ciliary body involvement, can achieve exceptional survival and visual recovery through targeted therapy. This case suggests ocular biopsy and early molecular testing may refine management for similar patients. The unexpected treatment response warrants further studies on tumor-ocular microenvironment interactions.

Frontiers in MedicineVol. 12
Sichuan University (CN), West China Hospital of Sichuan University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Sichuan Province
Openalex Percentile: Top 58%
Ocular Oncology and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Case Report: Therapeutic biopsy guided targeted therapy improves visual acuity and prolongs survival in bilateral uveal metastases as the initial presentation of lung adenocarcinoma — Tongwen Ou, Chengda Ren, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS