Case Report: Therapeutic biopsy guided targeted therapy improves visual acuity and prolongs survival in bilateral uveal metastases as the initial presentation of lung adenocarcinoma
This case underscores that bilateral uveal metastasis, even with ciliary body involvement, can achieve exceptional survival and visual recovery through targeted therapy. This case suggests ocular biopsy and early molecular testing may refine management for similar patients. The unexpected treatment response warrants further studies on tumor-ocular microenvironment interactions.
Authors
- Tongwen Ou (ORCID: https://orcid.org/0000-0001-8055-9418)
- Chengda Ren (ORCID: https://orcid.org/0000-0002-5381-4265)
- Yiliu Yang (ORCID: https://orcid.org/0000-0002-5107-8604)
- Fang Lu
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-10-10
- DOI
- https://doi.org/10.3389/fmed.2025.1643966
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Sichuan Province