Exploring the Anticancer Efficacy of Tinospora Cordifolia: Revolutionizing Cancer Care Through Herbal Science

Cancer continues to be one of the most impactful causes of morbidity & motility changes at the global level and it marked by the uncontrolled cell division of anomalous cell, however common treatment, like chemotherapy and radiation therapy, have a played important role, they have an effect beside of unwanted side effect, which allows researching an alternative therapies, a famous and traditional medicinal herb in Ayurveda medicine, tinospora cordifoila, it has acquired importance in the field of cancer treatment as it include various bio-active molecule such as alkaloids, glycosides, and diterpenoid lactones. In this review, we summarize the regulatory or modulating roles of Tinospora cordifolia on major molecular pathways, including NF-κB, apoptosis, angiogenesis inhibition, and help immune response have anticancer potential. In vitro & some limited clinical studies show efficacy against Breast, cervical, and brain cancer with very list side effects. But more large-scale clinical studies are needed to confirm its safety and efficacy in the human population.

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Publication Details

Published
2025-10-09
DOI
https://doi.org/10.38124/ijisrt/25sep1486
Primary Topic
Phytochemicals and Medicinal Plants
Type
article
Field-Weighted Citation Impact
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article

Exploring the Anticancer Efficacy of Tinospora Cordifolia: Revolutionizing Cancer Care Through Herbal Science

R. Ram, C. Sharma, Roshan Gupta
Phytochemicals and Medicinal Plants
article

Exploring the Anticancer Efficacy of Tinospora Cordifolia: Revolutionizing Cancer Care Through Herbal Science

R. Ram, C. Sharma, Roshan Gupta
article en

Abstract

Cancer continues to be one of the most impactful causes of morbidity & motility changes at the global level and it marked by the uncontrolled cell division of anomalous cell, however common treatment, like chemotherapy and radiation therapy, have a played important role, they have an effect beside of unwanted side effect, which allows researching an alternative therapies, a famous and traditional medicinal herb in Ayurveda medicine, tinospora cordifoila, it has acquired importance in the field of cancer treatment as it include various bio-active molecule such as alkaloids, glycosides, and diterpenoid lactones. In this review, we summarize the regulatory or modulating roles of Tinospora cordifolia on major molecular pathways, including NF-κB, apoptosis, angiogenesis inhibition, and help immune response have anticancer potential. In vitro & some limited clinical studies show efficacy against Breast, cervical, and brain cancer with very list side effects. But more large-scale clinical studies are needed to confirm its safety and efficacy in the human population.

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Phytochemicals and Medicinal Plants
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