Is calprotectin a reliable marker in surgical ICU settings? A clinical evaluation of its role in sepsis and mortality prediction

Calprotectin alone lacks sufficient diagnostic or prognostic power for sepsis in surgical ICU patients. It may serve as a complementary marker alongside PCT in specific subgroups.

Authors

Ebru Aladağ (ORCID: https://orcid.org/0000-0001-7219-1406)
Muhammed Emin Zora
Gültekin Yücel (ORCID: https://orcid.org/0000-0002-1974-1242)
Soycan Mızrak (ORCID: https://orcid.org/0000-0003-0287-9402)

Institutions

Usak University (TR)
Alanya University (TR)
Department of Public Health (MM)
Türk Anesteziyoloji ve Reanimasyon Derneği (TR)
Imation (United States) (US)
Adnan Menderes University (TR)

Publication Details

Journal: Frontiers in Medicine
Published: 2025-10-10
DOI: https://doi.org/10.3389/fmed.2025.1619825
Primary Topic: Sepsis Diagnosis and Treatment
Type: article
Field-Weighted Citation Impact: 0.00

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article

Is calprotectin a reliable marker in surgical ICU settings? A clinical evaluation of its role in sepsis and mortality prediction

Ebru Aladağ, Muhammed Emin Zora, Gültekin Yücel, Soycan Mızrak

Oct 10, 2025

Frontiers in Medicine

Sepsis Diagnosis and Treatment

article

Is calprotectin a reliable marker in surgical ICU settings? A clinical evaluation of its role in sepsis and mortality prediction

Ebru Aladağ, Muhammed Emin Zora, Gültekin Yücel, Soycan Mızrak

October 10, 2025article en

Abstract

Calprotectin alone lacks sufficient diagnostic or prognostic power for sepsis in surgical ICU patients. It may serve as a complementary marker alongside PCT in specific subgroups.

Frontiers in MedicineVol. 12

Usak University (TR), Alanya University (TR), Department of Public Health (MM), Türk Anesteziyoloji ve Reanimasyon Derneği (TR), Imation (United States) (US), Adnan Menderes University (TR)

Openalex Percentile: Top 62%

Sepsis Diagnosis and Treatment

DOI Open Access PDF OpenAlex

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Is calprotectin a reliable marker in surgical ICU settings? A clinical evaluation of its role in sepsis and mortality prediction — Ebru Aladağ, Muhammed Emin Zora, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS