Multi-omics integration to identify immune-associated biomarkers and potential therapeutics in periodontitis

Through integrating s transcriptomic and DNA methylation profiles, nine genes have been filtered as potential diagnostic biomarkers of periodontitis. Drugs targeting these genes may serve as potential therapeutics for periodontitis. These findings reveal valuable insights into immune and epigenetic mechanisms in periodontitis, presenting new biomarkers and therapeutic options that may enhance clinical diagnosis and treatment of the disease and provide unique insights for further exploration of the pathogenesis of periodontitis and the development of related therapeutic drugs.