Malignant neoplasms of the central nervous system of the PA Mayak personnel

The objective is to study the incidence of malignant tumors of the central nervous system of the personnel of the Mayak production association. Material and Methods: The study used data from the medical and dosimetric personnel register of the “Mayak” production association personnel hired in 1948-2016 and the cancer population register of the city of Ozyorsk. An assessment of the standardized ratio of morbidity rates among the city's population and the staff of the Mayak production association was carried out. Results and Discussion: During the follow-up period from 1948 to 2017, 220 cases of malignant neoplasms of the central nervous system were registered in the city of Ozyorsk, of which 70 cases were among the Mayak production association workers included in the medical dosimetric register (57 cases among male staff, 13 among female employees). Malignant brain tumors prevailed in the structure of the studied lesions (87.1 %), the most common lesions affected several areas of the brain (28.5 %) and the temporal lobe (14.3 %). No cases of malignant tumors of the central nervous system were recorded among male staff until 1960, and until 1980 among female staff. The age-standardized ratio of the incidence of malignant tumors of the central nervous system among the staff of Mayak and the population of Ozyorsk in men was 1.00 (95 % CI: 0.76; 1.29), in women – 0.91 (95 % CI: 0.48; 1.56). The estimates obtained turned out to be statistically indistinguishable from the unit, which indicates that there are no differences in the incidence rates of the population of Ozyorsk as a whole and the staff of the Mayak production association as a part of it. Conclusion: The results of the study confirm the previously obtained data on the absence of the influence of the occupational radiation factor on the incidence of malignant neoplasms of the central nervous system of the population of the city of Ozyorsk, including the staff of Mayak production association.