Severe Hyponatremia in the Emergency Department Incidence of Cerebral Edema and Risk of Osmotic Demyelination Syndrome

Given the low rate of cerebral edema even in severely symptomatic patients, aggressive treatment may not be necessary in most cases. The risk to develop ODS seems to be higher than the risk of brain edema. Since we found no beneficial impact of a liberal correction strategy, current treatment limits should stay in place.

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Publication Details

Journal
Academic Emergency Medicine
Published
2025-10-09
DOI
https://doi.org/10.1111/acem.70158
Citations
1
Primary Topic
Electrolyte and hormonal disorders
Type
article
Field-Weighted Citation Impact
1.52
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article

Severe Hyponatremia in the Emergency Department Incidence of Cerebral Edema and Risk of Osmotic Demyelination Syndrome

Matthias J. Hackl, Sadrija Cukoski, Thorsten Persigehl, R Rabii et al.
1 citations
Academic Emergency Medicine
Electrolyte and hormonal disorders
1.52
article

Severe Hyponatremia in the Emergency Department Incidence of Cerebral Edema and Risk of Osmotic Demyelination Syndrome

Matthias J. Hackl, Sadrija Cukoski, Thorsten Persigehl, R Rabii, Volker Burst, Christoph Hüser, Kathrin Möllenhoff, Víctor Suárez, Stefan Haneder, Moritz Trappe, Julian Peto‐Madew
article en
1 citations

Abstract

Given the low rate of cerebral edema even in severely symptomatic patients, aggressive treatment may not be necessary in most cases. The risk to develop ODS seems to be higher than the risk of brain edema. Since we found no beneficial impact of a liberal correction strategy, current treatment limits should stay in place.

Academic Emergency MedicineVol. 33(1)
University of Cologne (DE), University Hospital Cologne (DE)
Openalex Percentile: Top 14%
Electrolyte and hormonal disorders
1.52
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Severe Hyponatremia in the Emergency Department Incidence of Cerebral Edema and Risk of Osmotic Demyelination Syndrome — Matthias J. Hackl, Sadrija Cukoski, et al. · Academic Emergency Medicine (2025) | TGRS Research Map | TGRS