Development of a clinical risk scoring system for artesunate treatment failure prediction in malaria patients
Parasitemia >5 %, impaired consciousness, and female sex were predictive of artesunate treatment failure as defined by WHO clinical criteria. The developed risk scoring system provides a practical tool for identifying high-risk patients requiring intensified monitoring and alternative treatment strategies. These findings are derived from a South Korean cohort and should be interpreted with caution when extrapolated to endemic populations.
Authors
- Hye Sun Gwak (ORCID: https://orcid.org/0000-0003-0278-2563)
- David D. Lee (ORCID: https://orcid.org/0000-0002-2086-0150)
- Jung‐Sun Kim (ORCID: https://orcid.org/0000-0003-2263-3274)
- Dasom Kim (ORCID: https://orcid.org/0000-0002-7817-3652)
- Yubin Song (ORCID: https://orcid.org/0000-0001-6933-2642)
Institutions
- Ewha Womans University (KR)
- Kangwon National University (KR)
Publication Details
- Journal
- International Journal for Parasitology Drugs and Drug Resistance
- Published
- 2025-10-10
- DOI
- https://doi.org/10.1016/j.ijpddr.2025.100621
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00