Multipotent adult progenitor cell therapy: Effect of timing and frequency on lung health in preterm lambs during inflammation

All three MAPC regimens improve preterm lung outcomes under inflammatory conditions. However, mechanisms underlying stem cell therapy are modulated in a time- and insult-dependent manner, highlighting the potential of stem cell therapy as personalized approach.

Authors

Institutions

Publication Details

Journal
Pharmacological Research
Published
2025-10-10
DOI
https://doi.org/10.1016/j.phrs.2025.107979
Primary Topic
Neonatal Respiratory Health Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Multipotent adult progenitor cell therapy: Effect of timing and frequency on lung health in preterm lambs during inflammation

Tim Brokken, Luc J. I. Zimmermann, Daan R. M. G. Ophelders, Helene Widowski et al.
Pharmacological Research
Neonatal Respiratory Health Research
article

Multipotent adult progenitor cell therapy: Effect of timing and frequency on lung health in preterm lambs during inflammation

Tim Brokken, Luc J. I. Zimmermann, Daan R. M. G. Ophelders, Helene Widowski, Shahab Jolani, Matthias Christian Hütten, Ilse H. de Lange, Mireille M.J.P.E. Sthijns, C. Severens‐Rijvers, Vanessa L.S. LaPointe, Charlotte van Gorp, Niki L. Reynaert, Christof Seiler, J. Jane Pillow, Tim G. A. M. Wolfs, Tammo Delhaas, Sophie M. L. Neuen, Peter G. J. Nikkels
article en

Abstract

All three MAPC regimens improve preterm lung outcomes under inflammatory conditions. However, mechanisms underlying stem cell therapy are modulated in a time- and insult-dependent manner, highlighting the potential of stem cell therapy as personalized approach.

Pharmacological ResearchVol. 221
The University of Western Australia (AU), Maastricht University Medical Centre (NL), United Nations University – Maastricht Economic and Social Research Institute on Innovation and Technology (NL), University Medical Center Utrecht (NL), Maastricht University (NL), Department of Health (TW)
Openalex Percentile: Top 59%
Neonatal Respiratory Health Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Multipotent adult progenitor cell therapy: Effect of timing and frequency on lung health in preterm lambs during inflammation — Tim Brokken, Luc J. I. Zimmermann, et al. · Pharmacological Research (2025) | TGRS Research Map | TGRS