Integrated proteomic and metabolomic analysis elucidates the effects and mechanisms of Qiziyusi decoction on IVF outcomes in advanced maternal age infertility
QZYSD in IVF for women with AMA infertility is promising for improving clinical pregnancy rates and overall IVF outcomes, potentially through its effect on the FF microenvironment. However, further research is needed to conduct larger randomized controlled double-blind clinical trials and experimental studies to elucidate the efficacy and mechanisms of QZYSD on IVF success in this population.
Authors
- Jingyan Song (ORCID: https://orcid.org/0000-0001-7269-680X)
- Qingchun Jin (ORCID: https://orcid.org/0000-0001-6388-5123)
- Xianling Cao (ORCID: https://orcid.org/0000-0001-9544-7419)
- Zhen‐Gao Sun (ORCID: https://orcid.org/0000-0002-9723-1213)
- Yingjie Ma (ORCID: https://orcid.org/0000-0002-6692-5992)
- Jianyun Zhao (ORCID: https://orcid.org/0000-0003-0137-6037)
- Menghan Yan
- Yi Zhang (ORCID: https://orcid.org/0000-0002-0745-3497)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-10
- DOI
- https://doi.org/10.3389/fendo.2025.1573206
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Natural Science Foundation of Shandong Province
- National Key Research and Development Program of China