Identification of potential biomarkers for breast cancer based on salivary metabolomics

The salivary metabolome of breast cancer patients displays distinct changes compared to healthy individuals. Salivary 2-aminonicotinic acid and theobromine emerge as promising non-invasive biomarkers for breast cancer detection. Nevertheless, larger-scale validation studies are warranted to substantiate their specificity and clinical utility.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-10-10
DOI
https://doi.org/10.3389/fonc.2025.1655213
Citations
2
Primary Topic
Metabolomics and Mass Spectrometry Studies
Type
article
Field-Weighted Citation Impact
1.61
Controls
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article

Identification of potential biomarkers for breast cancer based on salivary metabolomics

Yang Li, Kai Ming Yang, Xinyu Jiang, Yumei Jia et al.
2 citations
Frontiers in Oncology
Metabolomics and Mass Spectrometry Studies
1.61
article

Identification of potential biomarkers for breast cancer based on salivary metabolomics

Yang Li, Kai Ming Yang, Xinyu Jiang, Yumei Jia, Bo Zhang
article en
2 citations

Abstract

The salivary metabolome of breast cancer patients displays distinct changes compared to healthy individuals. Salivary 2-aminonicotinic acid and theobromine emerge as promising non-invasive biomarkers for breast cancer detection. Nevertheless, larger-scale validation studies are warranted to substantiate their specificity and clinical utility.

Frontiers in OncologyVol. 15
Central South University (CN), Hunan University of Traditional Chinese Medicine (CN), Hunan Cancer Hospital (CN)
Openalex Percentile: Top 14%
Metabolomics and Mass Spectrometry Studies
1.61
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Identification of potential biomarkers for breast cancer based on salivary metabolomics — Yang Li, Kai Ming Yang, et al. · Frontiers in Oncology (2025) | TGRS Research Map | TGRS