Aztreonam intervention recalibrates microbial interactions between Pseudomonas aeruginosa and Streptococcus salivarius
This study suggests that the repeated use of antibiotics may contribute to the persistent coexistence of polymicrobial communities within the host, leading to complex microbial dynamics that impact disease progression. It underscores the critical need to explore bacterial interactions in detail, as understanding these relationships could revolutionize our approach to chronic diseases caused by polymicrobial infections, offering new therapeutic strategies that go beyond traditional pathogen-targeted treatments.
Authors
- Ming Feng (ORCID: https://orcid.org/0000-0001-7320-0378)
- Ting Huang (ORCID: https://orcid.org/0000-0002-2943-588X)
- Yiwen Chu (ORCID: https://orcid.org/0000-0002-9152-0866)
- Xiting Yang (ORCID: https://orcid.org/0000-0002-6997-7448)
- Kelei Zhao (ORCID: https://orcid.org/0000-0002-2515-065X)
- Shiyi Gou
- Yi Wu (ORCID: https://orcid.org/0000-0001-9281-7891)
- Yang Yuan (ORCID: https://orcid.org/0000-0003-0690-568X)
- Xin Hu
Institutions
- Sichuan University (CN)
- Chengdu University (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-10-10
- DOI
- https://doi.org/10.1186/s12866-025-04303-x
- Primary Topic
- Bacterial biofilms and quorum sensing
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Chengdu University