Integrated fibre-specific methylome and proteome profiling of human skeletal muscle across males and females with fibre-type deconvolution
We provide integrated methylome and proteome profiles of human muscle fibre-types generalisable to both male and females as a freely accessible interactive repository, MyoMETH ( https://myometh.net ), allowing further investigation into fibre regulation. Data are available via ProteomeXchange with identifier PXD066393 and the Gene Expression Omnibus at GSE304045 .
Authors
- Kirsten Seale (ORCID: https://orcid.org/0000-0003-3048-7983)
- Nir Eynon (ORCID: https://orcid.org/0000-0003-4046-8276)
- Megan F. Taylor (ORCID: https://orcid.org/0000-0002-2922-0379)
- Esther García-Domínguez (ORCID: https://orcid.org/0000-0001-6276-4944)
- Joel R. Steele (ORCID: https://orcid.org/0000-0002-3070-9761)
- Andrew Garnham (ORCID: https://orcid.org/0000-0001-8068-9300)
- Han-Chung Lee (ORCID: https://orcid.org/0000-0002-9858-757X)
- Ralf B. Schittenhelm (ORCID: https://orcid.org/0000-0001-8738-1878)
- Andrew S. Palmer
Institutions
- Walter and Eliza Hall Institute of Medical Research (AU)
- Discovery Institute (US)
- Centenary Institute (AU)
- Australian Regenerative Medicine Institute (AU)
- Monash University (AU)
- Victoria University (AU)
Publication Details
- Journal
- Skeletal Muscle
- Published
- 2025-10-10
- DOI
- https://doi.org/10.1186/s13395-025-00396-0
- Citations
- 1
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Health and Medical Research Council