Comparative evaluation of single- and multi-delay arterial spin labeling MRI in preterm neonates
Multi-delay ASL is the favorable technique for neonatal neuroimaging based on image quality and hemodynamic measurements. Sex- and age-related hemodynamic variations underscore the importance of techniques distinguishing ATT and CBF components for improved neonatal perfusion neuroimaging. Despite frequent motion artifacts, ASL quality was comparable to structural scans. These findings support broader clinical adoption of multi-delay ASL in neonatal imaging protocols.
Authors
- Elizabeth Tong (ORCID: https://orcid.org/0000-0002-9550-8178)
- Kristen W. Yeom (ORCID: https://orcid.org/0000-0001-9860-3368)
- Gary K. Steinberg (ORCID: https://orcid.org/0000-0001-6374-1058)
- Moss Zhao (ORCID: https://orcid.org/0000-0002-0210-7739)
- Martin Kynčl (ORCID: https://orcid.org/0000-0001-6210-6351)
- Yeva Prysiazhniuk (ORCID: https://orcid.org/0000-0001-7384-1693)
- Michael E. Moseley (ORCID: https://orcid.org/0000-0002-9163-8741)
- Suceena Alexander (ORCID: https://orcid.org/0000-0001-7692-606X)
- Rui Duarte Armindo (ORCID: https://orcid.org/0000-0003-0001-742X)
- Jakub Otáhal (ORCID: https://orcid.org/0000-0001-5944-5803)
- Jan Petr (ORCID: https://orcid.org/0000-0002-3201-6002)
Institutions
- Charles University (CZ)
- Helmholtz-Zentrum Dresden-Rossendorf (DE)
- University Hospital in Motol (CZ)
- Western NSW Local Health District (AU)
- Stanford Medicine (US)
- Stanford University (US)
Publication Details
- Journal
- NeuroImage
- Published
- 2025-10-10
- DOI
- https://doi.org/10.1016/j.neuroimage.2025.121511
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Heart Association
- European Commission
- Ministerstvo Školství, Mládeže a Tělovýchovy
- Agentura Pro Zdravotnický Výzkum České Republiky
- HORIZON EUROPE Framework Programme
- Stanford Maternal and Child Health Research Institute