Exploring the impact of antibody-dependent cellular phagocytosis-related genes on the prognosis of metastatic melanoma
The model also demonstrated associations with immune cell infiltration and drug sensitivity, highlighting its potential utility in optimizing immunotherapy and chemotherapy strategies. This study developed a novel ARG-based prognostic model that aids in survival prediction and therapeutic decision-making for metastatic melanoma patients. DOCK10 was identified as a potential therapeutic target in melanoma metastasis.
Authors
- Jia‐Peng He (ORCID: https://orcid.org/0000-0002-3061-3946)
- Xiaolong Xu (ORCID: https://orcid.org/0000-0003-3333-0906)
- Haiyan Sun (ORCID: https://orcid.org/0000-0001-9254-714X)
- Junhao Chen (ORCID: https://orcid.org/0000-0001-9577-1710)
- Jianglin Zhang (ORCID: https://orcid.org/0000-0002-6701-2044)
Institutions
- Central South University (CN)
- Jinan University (CN)
- Southern University of Science and Technology (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Xiangya Hospital Central South University (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1371/journal.pone.0333916
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00