Unveiling the oncogenic role of lncRNA PIG13-DT in hepatocellular carcinoma progression
Our study identifies a novel PIG13-DT/YBX3/USP15 axis driving HCC progression, suggesting PIG13-DT as a potential biomarker and therapeutic target. This work provides new insights into HCC molecular mechanisms and offers potential diagnostic and therapeutic implications.
Authors
- Zhiqiang Wu (ORCID: https://orcid.org/0000-0002-1800-9527)
- Shuqin Huang
- Hongjie Cai (ORCID: https://orcid.org/0000-0001-9666-3172)
- Fan Wang (ORCID: https://orcid.org/0000-0001-9806-5037)
- Dan Zeng (ORCID: https://orcid.org/0000-0002-3610-1618)
- Wenbo Guo (ORCID: https://orcid.org/0000-0002-1017-4640)
- Dongbing Li (ORCID: https://orcid.org/0000-0002-5227-9643)
- Feng Shi (ORCID: https://orcid.org/0000-0003-3509-3473)
- Song Chen (ORCID: https://orcid.org/0000-0002-5276-3953)
- Shao-Tong Tang
Institutions
- Sun Yat-sen University (CN)
- Soochow University (CN)
- ShenZhen People’s Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Guangdong Academy of Medical Sciences (CN)
- Sun Yat-sen University Cancer Center (CN)
- Union Hospital (US)
- Huazhong University of Science and Technology Hospital (CN)
- Eighth Affiliated Hospital of Sun Yat-sen University
Publication Details
- Journal
- Cancer Biology & Therapy
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1080/15384047.2025.2567797
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00