Post-ERCP Bowel Evisceration in a Liver Transplant Recipient Previously Treated with Atezolizumab�Bevacizumab: First Report

Hepatocellular carcinoma (HCC) treatment increasingly involves liver transplantation (LT), often after downstaging therapies. Atezolizumab, a PD-L1 inhibitor, combined with bevacizumab, an anti-VEGF agent, is widely used, showing high response rates pre-transplant. However, bevacizumab impairs angiogenesis and can significantly increase the risk of wound dehiscence, infection, and delayed healing after major surgery, including LT.

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Publication Details

Journal
Revista Española de Enfermedades Digestivas
Published
2025-01-01
DOI
https://doi.org/10.17235/reed.2025.11518/2025
Citations
1
Primary Topic
Gastrointestinal disorders and treatments
Type
article
Field-Weighted Citation Impact
2.01
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article

Post-ERCP Bowel Evisceration in a Liver Transplant Recipient Previously Treated with Atezolizumab�Bevacizumab: First Report

Cécile Gomercic, Maxime Thobois, Michel Rayar, Geoffroy Vanbiervliet et al.
1 citations
Revista Española de Enfermedades Digestivas
Gastrointestinal disorders and treatments
2.01
article

Post-ERCP Bowel Evisceration in a Liver Transplant Recipient Previously Treated with Atezolizumab�Bevacizumab: First Report

Cécile Gomercic, Maxime Thobois, Michel Rayar, Geoffroy Vanbiervliet, Dann Ouizeman, Elena Santos-Pérez, Rodolphe Anty, Anne-Claire Frin
article en
1 citations

Abstract

Hepatocellular carcinoma (HCC) treatment increasingly involves liver transplantation (LT), often after downstaging therapies. Atezolizumab, a PD-L1 inhibitor, combined with bevacizumab, an anti-VEGF agent, is widely used, showing high response rates pre-transplant. However, bevacizumab impairs angiogenesis and can significantly increase the risk of wound dehiscence, infection, and delayed healing after major surgery, including LT.

Revista Española de Enfermedades DigestivasVol. 118(2)
Université Côte d'Azur (FR), Centre Hospitalier Universitaire de Nice (FR), Cognition Behaviour Technology (FR)
Openalex Percentile: Top 11%
Gastrointestinal disorders and treatments
2.01
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