Prevention of Severe Postoperative Pain after Breast Surgery Using Opioid-Sparing Analgesia with Intraoperative and Drain-Based Ropivacaine Infiltration: A Prospective Observational Study

Intraoperative and drain-based ropivacaine wound infiltration, alone or in combination with pre-emptive oxycodone, effectively reduced acute postoperative pain and opioid requirements after breast surgery, while reducing opioid-related side effects like nausea and vomiting. As part of a multimodal, opioid-sparing strategy, this technique demonstrated favourable patient-reported outcomes and may contribute to faster recovery, fewer side effects, and improved patient-reported satisfaction. These findings support the clinical relevance of preventive local anaesthetic techniques in breast surgery.

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Publication Details

Journal
Breast Care
Published
2025-10-09
DOI
https://doi.org/10.1159/000547185
Primary Topic
Anesthesia and Pain Management
Type
article
Field-Weighted Citation Impact
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article

Prevention of Severe Postoperative Pain after Breast Surgery Using Opioid-Sparing Analgesia with Intraoperative and Drain-Based Ropivacaine Infiltration: A Prospective Observational Study

Ingo B. Runnebaum, J Jiménez Cruz, Norah Emrich, Winfried Meißner et al.
Breast Care
Anesthesia and Pain Management
article

Prevention of Severe Postoperative Pain after Breast Surgery Using Opioid-Sparing Analgesia with Intraoperative and Drain-Based Ropivacaine Infiltration: A Prospective Observational Study

Ingo B. Runnebaum, J Jiménez Cruz, Norah Emrich, Winfried Meißner, Florian Röser, Angela Kather, Kristin Nicolaus-Tellenbach
article en

Abstract

Intraoperative and drain-based ropivacaine wound infiltration, alone or in combination with pre-emptive oxycodone, effectively reduced acute postoperative pain and opioid requirements after breast surgery, while reducing opioid-related side effects like nausea and vomiting. As part of a multimodal, opioid-sparing strategy, this technique demonstrated favourable patient-reported outcomes and may contribute to faster recovery, fewer side effects, and improved patient-reported satisfaction. These findings support the clinical relevance of preventive local anaesthetic techniques in breast surgery.

Breast Care
University Hospital Bonn (DE), Jena University Hospital (DE), Sozialstiftung Bamberg (DE), Friedrich Schiller University Jena (DE)
Openalex Percentile: Top 55%
Anesthesia and Pain Management
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Prevention of Severe Postoperative Pain after Breast Surgery Using Opioid-Sparing Analgesia with Intraoperative and Drain-Based Ropivacaine Infiltration: A Prospective Observational Study — Ingo B. Runnebaum, J Jiménez Cruz, et al. · Breast Care (2025) | TGRS Research Map | TGRS