Utility of hyperpolarised xenon-129 magnetic resonance imaging in primary ciliary dyskinesia
Xe MRI is a feasible imaging modality to capture lung disease in PCD. VDP has excellent same-day repeatability and correlated strongly with LCI<sub>2.5</sub>. Moreover, VDP was more sensitive at detecting lung function impairments than LCI<sub>2.5</sub> and FEV<sub>1</sub>z, demonstrating its potential as a sensitive outcome measure in PCD.
Authors
- Samal Munidasa (ORCID: https://orcid.org/0000-0001-5948-6234)
- Sharon Dell (ORCID: https://orcid.org/0000-0003-2169-9407)
- Félix Ratjen (ORCID: https://orcid.org/0000-0003-4057-6592)
- Rachel L. Eddy (ORCID: https://orcid.org/0000-0002-2541-1645)
- Brandon Zanette (ORCID: https://orcid.org/0000-0001-5645-0180)
- Wallace B. Wee (ORCID: https://orcid.org/0000-0003-4291-3513)
- Giles Santyr (ORCID: https://orcid.org/0000-0001-7396-188X)
- Jonathan H. Rayment (ORCID: https://orcid.org/0000-0003-4955-8876)
- Teresa To
Institutions
- University of Toronto (CA)
- Hospital for Sick Children (CA)
- Public Health Ontario (CA)
- SickKids Foundation (CA)
- Institute for Clinical Evaluative Sciences (CA)
- BC Children's Hospital (CA)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1183/23120541.01105-2025
- Primary Topic
- Atomic and Subatomic Physics Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00