Diffusing capacity of the lung for carbon monoxide, transfer coefficient of the lung for carbon monoxide and forced vital capacity/diffusing capacity of the lung for carbon monoxide in suspected systemic sclerosis-associated pulmonary hypertension: i

D LCO performed as least as strongly as K CO or FVC%/ D LCO% in terms of correlations with mean pulmonary arterial pressure and diagnostic utility, regardless of the presence or absence of lung disease. Transitioning to GLI equations led to lower predicted spirometric volumes and higher D LCO%. This should be considered when interpreting changes in values over time and when using screening algorithms.

Authors

Krit Dwivedi (ORCID: https://orcid.org/0000-0003-4949-4550)
Alexander Rothman (ORCID: https://orcid.org/0000-0002-7847-4500)
Howard D. Smith
David Gerard Kiely (ORCID: https://orcid.org/0000-0003-0184-6502)
Smitha Rajaram (ORCID: https://orcid.org/0000-0001-5010-2353)
Catherine Hill (ORCID: https://orcid.org/0000-0001-8289-4922)
Judith Hurdman (ORCID: https://orcid.org/0000-0003-0772-678X)
Rachael Kilding
Andrew J. Swift (ORCID: https://orcid.org/0000-0002-7903-5032)
Athanasios Charalampopoulos (ORCID: https://orcid.org/0000-0001-7281-9507)
Robin Condliffe (ORCID: https://orcid.org/0000-0002-3492-4143)
A. A. Roger Thompson (ORCID: https://orcid.org/0000-0002-0717-4551)
Samer Alabed (ORCID: https://orcid.org/0000-0002-9960-7587)
Abdul Hameed (ORCID: https://orcid.org/0000-0002-2128-2081)
Ashraful Haque (ORCID: https://orcid.org/0000-0003-2558-6653)
Mohammed Akil (ORCID: https://orcid.org/0000-0002-6813-4289)
Ian Smith
Charlie Elliot
Catherine Billings
Neil Hamilton
Kar-Ping Kuet (ORCID: https://orcid.org/0009-0006-2693-9165)

Institutions

Royal Hallamshire Hospital (GB)
Insigneo (GB)
University of Sheffield (GB)

Publication Details

Journal: ERJ Open Research
Published: 2025-10-09
DOI: https://doi.org/10.1183/23120541.00798-2025
Primary Topic: Systemic Sclerosis and Related Diseases
Type: article
Field-Weighted Citation Impact: 0.00

Diffusing capacity of the lung for carbon monoxide, transfer coefficient of the lung for carbon monoxide and forced vital capacity/diffusing capacity of the lung for carbon monoxide in suspected systemic sclerosis-associated pulmonary hypertension: i

Krit Dwivedi, Alexander Rothman, Howard D. Smith, David Gerard Kiely, Smitha Rajaram, Catherine Hill, Judith Hurdman, Rachael Kilding, Andrew J. Swift, Athanasios Charalampopoulos, Robin Condliffe, A. A. Roger Thompson, Samer Alabed, Abdul Hameed, Ashraful Haque, Mohammed Akil, Ian Smith, Charlie Elliot, Catherine Billings, Neil Hamilton, Kar-Ping Kuet

October 9, 2025article en

Diffusing capacity of the lung for carbon monoxide, transfer coefficient of the lung for carbon monoxide and forced vital capacity/diffusing capacity of the lung for carbon monoxide in suspected systemic sclerosis-associated pulmonary hypertension: i

Authors

Institutions

Publication Details

Diffusing capacity of the lung for carbon monoxide, transfer coefficient of the lung for carbon monoxide and forced vital capacity/diffusing capacity of the lung for carbon monoxide in suspected systemic sclerosis-associated pulmonary hypertension: i

Diffusing capacity of the lung for carbon monoxide, transfer coefficient of the lung for carbon monoxide and forced vital capacity/diffusing capacity of the lung for carbon monoxide in suspected systemic sclerosis-associated pulmonary hypertension: i

Abstract

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