Insulin-like growth factor binding protein 2 (IGFBP-2) as prognostic parameter in infarct-related cardiogenic shock
In AMI-CS, elevated levels of IGFBP-2 were associated with higher mortality at 30 days and one year after admission. IGFBP-2 represents a promising prognostic biomarker and could add value to risk stratification in this high-risk patient cohort, potentially informing early clinical decision-making.
Authors
- Petra Büttner (ORCID: https://orcid.org/0000-0003-0799-4725)
- Norbert Gerdes (ORCID: https://orcid.org/0000-0002-4546-7208)
- Malte Kelm (ORCID: https://orcid.org/0000-0003-0060-1052)
- Christian Jung (ORCID: https://orcid.org/0000-0001-8325-250X)
- Anne Freund
- Uta Ceglarek (ORCID: https://orcid.org/0000-0002-4034-5535)
- Bernhard Wernly (ORCID: https://orcid.org/0000-0003-4024-0220)
- Maryna Masyuk (ORCID: https://orcid.org/0000-0003-2856-6893)
- İbrahim Akın (ORCID: https://orcid.org/0000-0003-1974-6147)
- Mara Schemmelmann
- Benedikt Schrage (ORCID: https://orcid.org/0000-0001-9041-3922)
- Steffen Schneider (ORCID: https://orcid.org/0000-0001-9375-4861)
- Uwe Zeymer (ORCID: https://orcid.org/0000-0001-7077-283X)
- Berend Isermann (ORCID: https://orcid.org/0000-0003-0714-6160)
- Steffen Desch (ORCID: https://orcid.org/0000-0002-9416-8044)
- Janine Pöss
- Georg Fürnau
- Holger Thiele
Institutions
- University of Freiburg (DE)
- University of Mannheim (DE)
- Heidelberg University (DE)
- Paracelsus Medical University (AT)
- University Hospital Heidelberg (DE)
- Düsseldorf University Hospital (DE)
- Städtisches Klinikum Dessau (DE)
- Stiftung Institut für Herzinfarktforschung (DE)
- Leipzig Heart Institute (DE)
- German Centre for Cardiovascular Research (DE)
- Universitäts-Herzzentrum Freiburg-Bad Krozingen (DE)
- Heinrich Heine University Düsseldorf (DE)
- Leipzig University (DE)
Publication Details
- Journal
- International Journal of Cardiology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1016/j.ijcard.2025.133961
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Deutsche Stiftung für Herzforschung
- Deutsche Gesellschaft für Kardiologie-Herz und Kreislaufforschung.