Impact of Vomer Flap on Nutritional Status in Infants With Cleft Lip and Palate: A Multicenter Retrospective Cohort Study

<i>Objective</i>To determine the effect of early hard palate closure by means of a Vomer flap (VF) on the nutritional status of children with cleft lip and palate.<i>Design</i>Multicenter retrospective cohort study.<i>Setting</i>Three referral centers for oral clefts.<i>Patients, Participants</i>Nonsyndromic children with UCLP or BCLP.<i>Interventions:</i> Early hard palate closure with a VF at cheiloplasty around 3 months versus isolated cheiloplasty, both followed by palatoplasty around 9 to 10 months.<i>Main Outcome Measure(s)</i>Anthropometric measures (weight and height) and related weight-for-age and height-for-age Z-scores at the time of cheiloplasty and palatoplasty.<i>Results</i>Between 2012 and 2024, 122 children with UCLP or BCLP underwent cleft repair surgery. Median age at cheiloplasty was 111 (99-126) days and 304 (284-342) at palatoplasty. In 60% of them (n = 73), a VF was performed simultaneously with cheiloplasty. Weight increase between cheiloplasty and palatoplasty was slightly more for the VF group compared to the control group by 0.24 kg (SE = 0.15, <i>P</i> = .13). No height difference was measured between the groups (<i>P</i> = .80). Z-score variation between cheiloplasty and palatoplasty was significantly different for all study groups, indicating a strong normalization of the growth curve after cheiloplasty (<i>P</i> < .001).<i>Conclusions</i>Early hard palate closure using a VF may favor growth in children with cleft lip and palate. The deviation from the normative growth curve of infants decreases significantly between cheiloplasty and palatoplasty, regardless of whether a VF was performed.

Authors

Institutions

Publication Details

Journal
The Cleft Palate-Craniofacial Journal
Published
2025-10-09
DOI
https://doi.org/10.1177/10556656251385010
Primary Topic
Cleft Lip and Palate Research
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Impact of Vomer Flap on Nutritional Status in Infants With Cleft Lip and Palate: A Multicenter Retrospective Cohort Study

Chantal M. Mouës-Vink, Corstiaan C. Breugem, Edith Visser, Sofia Bachini et al.
The Cleft Palate-Craniofacial Journal
Cleft Lip and Palate Research
article

Impact of Vomer Flap on Nutritional Status in Infants With Cleft Lip and Palate: A Multicenter Retrospective Cohort Study

Chantal M. Mouës-Vink, Corstiaan C. Breugem, Edith Visser, Sofia Bachini, Robin Delnoij
article en

Abstract

<i>Objective</i>To determine the effect of early hard palate closure by means of a Vomer flap (VF) on the nutritional status of children with cleft lip and palate.<i>Design</i>Multicenter retrospective cohort study.<i>Setting</i>Three referral centers for oral clefts.<i>Patients, Participants</i>Nonsyndromic children with UCLP or BCLP.<i>Interventions:</i> Early hard palate closure with a VF at cheiloplasty around 3 months versus isolated cheiloplasty, both followed by palatoplasty around 9 to 10 months.<i>Main Outcome Measure(s)</i>Anthropometric measures (weight and height) and related weight-for-age and height-for-age Z-scores at the time of cheiloplasty and palatoplasty.<i>Results</i>Between 2012 and 2024, 122 children with UCLP or BCLP underwent cleft repair surgery. Median age at cheiloplasty was 111 (99-126) days and 304 (284-342) at palatoplasty. In 60% of them (n = 73), a VF was performed simultaneously with cheiloplasty. Weight increase between cheiloplasty and palatoplasty was slightly more for the VF group compared to the control group by 0.24 kg (SE = 0.15, <i>P</i> = .13). No height difference was measured between the groups (<i>P</i> = .80). Z-score variation between cheiloplasty and palatoplasty was significantly different for all study groups, indicating a strong normalization of the growth curve after cheiloplasty (<i>P</i> < .001).<i>Conclusions</i>Early hard palate closure using a VF may favor growth in children with cleft lip and palate. The deviation from the normative growth curve of infants decreases significantly between cheiloplasty and palatoplasty, regardless of whether a VF was performed.

The Cleft Palate-Craniofacial Journal
Medisch Centrum Leeuwarden (NL), Amsterdam University Medical Centers (NL)
Openalex Percentile: Top 70%
Cleft Lip and Palate Research
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Impact of Vomer Flap on Nutritional Status in Infants With Cleft Lip and Palate: A Multicenter Retrospective Cohort Study — Chantal M. Mouës-Vink, Corstiaan C. Breugem, et al. · The Cleft Palate-Craniofacial Journal (2025) | TGRS Research Map | TGRS