Detection of leukemia gene fusions on DNA-level through targeted Next-Generation Sequencing
This study confirms the feasibility of employing tNGS methods to concurrently identify gene mutations and fusions (including IGH and MYC rearrangements) at the DNA level in adults with leukemia.
Authors
- Bin Chen (ORCID: https://orcid.org/0000-0002-1822-9984)
- Yani Lin (ORCID: https://orcid.org/0000-0003-4333-1670)
- Long Chen (ORCID: https://orcid.org/0000-0003-1110-6495)
- Jing Li (ORCID: https://orcid.org/0000-0002-2037-5817)
- Hong Zhang (ORCID: https://orcid.org/0000-0002-3249-0935)
- Zhihui Gao
Institutions
- Central Hospital of Zibo (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1371/journal.pone.0332407
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00