Gastrointestinal Survivability of a BSH-Positive Lacticaseibacillus rhamnosus VB4 Strain and Its Effect on Bile Acid Deconjugation in a Dynamic In Vitro Gut Model
These findings highlight the survivability of <i>L. rhamnosus</i> VB4 strain inside the gut and its potential as biotherapeutic BAs-mediator candidate, demonstrating that transcriptomic and metabolomic approaches coupled to a dynamic in vitro gut model represent a robust tool for selection of a BSH-positive probiotic candidate.
Authors
- Alice Cattivelli (ORCID: https://orcid.org/0000-0002-6841-3608)
- Lisa Solieri (ORCID: https://orcid.org/0000-0003-3546-6903)
- Gianluigi Agolino (ORCID: https://orcid.org/0009-0005-1610-8811)
- Alessandra Pino (ORCID: https://orcid.org/0000-0001-8246-106X)
- Amanda Vaccalluzzo (ORCID: https://orcid.org/0000-0002-4902-1799)
- Cinzia Caggia (ORCID: https://orcid.org/0000-0002-2688-9536)
- Cinzia Lucia Randazzo (ORCID: https://orcid.org/0000-0002-1243-5357)
- Davide Tagliazucchi (ORCID: https://orcid.org/0000-0002-6462-9305)
- Marianna Cristofolini
Institutions
- University of Modena and Reggio Emilia (IT)
- University of Catania (IT)
Publication Details
- Journal
- Nutrients
- Published
- 2025-10-08
- DOI
- https://doi.org/10.3390/nu17193179
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00