System of prevention of metabolic syndrome in horses using a complex of disinfectants and probiotics

The article discusses the results of research on the development of a system for the integrated use of a probiotic and two disinfectants in horse husbandry. The scheme, regimens and terms of application of spore probiotic in the feed and disinfectants in the presence of horses for 50 days for the prevention of metabolic syndrome are proposed. The doses and concentrations of the studied drugs are also summarized. The effect of the studied drugs on the hematological parameters of horses was analyzed. The results of the studies showed that feeding spore probiotics with feed and the use of disinfectants in their presence did not have a negative effect on the horse's body. Production studies have determined the modes of disinfection of horse farm premises in the presence of horses, using iodine-based disinfectants "Iodesol" and "Geocide" based on benzalkonium chloride and deltamethrin, and established a bactericidal effect when disinfecting walls, floors and feeders of the premises when used in aerosol form. For prophylaxis, after thorough mechanical cleaning of the surfaces of the premises of the experimental group, once every 2 weeks, disinfection was carried out with a 0.2 % solution of "Iodesol" at the rate of 0.3 l of solution per 1 m^2^ until complete drying at an exposure time of 30 minutes. Also, once a week, the premises were disinfected using a cold fog generator, using the aerosol method with a 0.5 % working solution of the Geocide preparation for a one-hour exposure at a consumption of 0.05 l/m^3^. Disinfection was carried out with ventilation turned on. Sanitary and hygienic studies were conducted according to current methods. The bactericidal effect when disinfecting the surface of the room in the presence of horses during their maintenance after disinfection with disinfectants "Iodesol" and "Geocide" was almost 100%, which confirms their effectiveness. Under the influence of the studied drugs, a positive effect on the blood parameters of horses was revealed. On day 35 of the study, the hemoglobin level in the experimental group exceeded the control values by 8.2 % (p<0.05), and on day 50 by 11.3 % (p<0.05). The number of red blood cells in the experimental group also increased during the same period: on day 35 it was 17.5% higher (p<0.01), and on day 50 by 12.2% (p<0.01) compared to the control. At the same time, no significant changes in the number of leukocytes and the ratio of their individual species in the blood of horses of the experimental group compared to the control group were found. These data indicate that aerosol treatment of premises in the presence of horses is not toxic and has no negative effect on the physiological state, which is confirmed by studies of blood morphological parameters.