Synthesis and Evaluation of Hydrogen-Bonding Organocatalysts Bearing P(V)-Stereogenic Centers

Abstract In this study, we report the synthesis of a novel series of chiral hybrid scaffolds, each featuring a P(V)-stereogenic center integrated with a chiral backbone via squaramide or thiourea linkers. The catalytic performance of these newly developed organocatalysts was evaluated in asymmetric transfer hydrogenation reactions, showing moderate activity and limited selectivity.

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Publication Details

Journal
Synthesis
Published
2025-10-09
DOI
https://doi.org/10.1055/a-2705-4396
Primary Topic
Asymmetric Synthesis and Catalysis
Type
article
Field-Weighted Citation Impact
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article

Synthesis and Evaluation of Hydrogen-Bonding Organocatalysts Bearing P(V)-Stereogenic Centers

Nadine Kreidt, Mathias Christmann, Zhen Wang
Synthesis
Asymmetric Synthesis and Catalysis
article

Synthesis and Evaluation of Hydrogen-Bonding Organocatalysts Bearing P(V)-Stereogenic Centers

Nadine Kreidt, Mathias Christmann, Zhen Wang
article en

Abstract

Abstract In this study, we report the synthesis of a novel series of chiral hybrid scaffolds, each featuring a P(V)-stereogenic center integrated with a chiral backbone via squaramide or thiourea linkers. The catalytic performance of these newly developed organocatalysts was evaluated in asymmetric transfer hydrogenation reactions, showing moderate activity and limited selectivity.

SynthesisVol. 57(24)
Berlin School of Economics and Law (DE)
Openalex Percentile: Top 78%
Asymmetric Synthesis and Catalysis
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