Placental mosaicism for structural chromosomal variants: follow-up of 251 Danish cases (1983–2021)
Mosaicism for an SV detected in CVS is associated with a high risk of TFM. CPM involving SV's does not generally appear to increase the risk of adverse outcomes, although a modestly elevated risk of preterm birth was observed in cases with overall chromosomal gains.
Authors
- Ida Vogel (ORCID: https://orcid.org/0000-0002-1125-0393)
- Simon Horsholt Thomsen
- Naja Becher (ORCID: https://orcid.org/0000-0003-1264-1940)
- Ida Charlotte Bay Lund (ORCID: https://orcid.org/0000-0001-5480-220X)
- Iben Bache (ORCID: https://orcid.org/0000-0001-7562-8546)
Institutions
- Aarhus University Hospital (DK)
- Rigshospitalet (DK)
Publication Details
- Journal
- Placenta
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1016/j.placenta.2025.10.006
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00