Hyalinizing Clear Cell Carcinoma of the Thymus Predominantly Composed of Eosinophilic Cells: A Case Report and Literature Review

Clear cell carcinoma of the thymus is a rare malignant neoplasm originating from the thymus. Hyalinizing clear cell carcinoma of the thymus is an exceptionally rare subtype and poses significant diagnostic challenges when predominantly composed of eosinophilic cells. Here, we present a case report of thymic hyalinizing clear cell carcinoma predominantly composed of eosinophilic cells, along with a comprehensive literature review analyzing its clinical, histopathological, immunohistochemical, and molecular characteristics.

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Journal
International Journal of Surgical Pathology
Published
2025-10-09
DOI
https://doi.org/10.1177/10668969251382663
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
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article

Hyalinizing Clear Cell Carcinoma of the Thymus Predominantly Composed of Eosinophilic Cells: A Case Report and Literature Review

Ying Zeng, Liping Luo, Liang Lv, Ping Fu
International Journal of Surgical Pathology
Myasthenia Gravis and Thymoma
article

Hyalinizing Clear Cell Carcinoma of the Thymus Predominantly Composed of Eosinophilic Cells: A Case Report and Literature Review

Ying Zeng, Liping Luo, Liang Lv, Ping Fu
article en

Abstract

Clear cell carcinoma of the thymus is a rare malignant neoplasm originating from the thymus. Hyalinizing clear cell carcinoma of the thymus is an exceptionally rare subtype and poses significant diagnostic challenges when predominantly composed of eosinophilic cells. Here, we present a case report of thymic hyalinizing clear cell carcinoma predominantly composed of eosinophilic cells, along with a comprehensive literature review analyzing its clinical, histopathological, immunohistochemical, and molecular characteristics.

International Journal of Surgical PathologyVol. 34(2)
Daping Hospital (CN), Third People 's Hospital of Chongqing (CN), Chongqing Public Health Medical Center (CN)
Openalex Percentile: Top 59%
Myasthenia Gravis and Thymoma
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Hyalinizing Clear Cell Carcinoma of the Thymus Predominantly Composed of Eosinophilic Cells: A Case Report and Literature Review — Ying Zeng, Liping Luo, et al. · International Journal of Surgical Pathology (2025) | TGRS Research Map | TGRS