Effects of pentoxifylline in patients with chronic Chagas cardiomyopathy: A randomized, double-blind, controlled pilot trial
The results of this study suggest a potential positive effect of PTX in modulating the inflammatory profile of CCC patients. However, use of pentoxifylline in these patients did not attenuate the degree of ventricular dysfunction or reduce myocardial perfusion defects.
Authors
- Antônio Carlos Leite de Barros Filho
- Denise Mayumi Tanaka (ORCID: https://orcid.org/0000-0002-5035-9172)
- José Antônio Marin‐Neto (ORCID: https://orcid.org/0000-0002-8651-8833)
- Henrique Turin Moreira (ORCID: https://orcid.org/0000-0002-4543-4684)
- Camila Godoy Fabricio (ORCID: https://orcid.org/0000-0001-6174-6939)
- Káryta Suely Macêdo Martins
- Marcus Vinı́cius Simões (ORCID: https://orcid.org/0000-0001-6553-8387)
- Paulo Louzada‐Júnior (ORCID: https://orcid.org/0000-0003-2585-3870)
Institutions
- Universidade de São Paulo (BR)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1371/journal.pntd.0013555
- Primary Topic
- Trypanosoma species research and implications
- Type
- article
- Field-Weighted Citation Impact
- 0.00