Viral metagenomic sequencing reveals rare pathogens and improves diagnostic accuracy in neuroinflammatory disorders
Viral metagenomic sequencing as a first-line diagnostic tool in combination with conventional methods yields the most comprehensive results to diagnose patients with infectious neuroinflammatory disorders. Its unbiased approach enables the detection of rare or unconsidered viruses.
Authors
- Ian Pichler (ORCID: https://orcid.org/0009-0002-6303-1544)
- Tobias Weiß (ORCID: https://orcid.org/0000-0002-5533-9429)
- Gabriela Ziltener
- Betsy Hirsch (ORCID: https://orcid.org/0000-0003-0162-6905)
- Patrick Roth (ORCID: https://orcid.org/0000-0003-3897-214X)
- David L. Weller
- Alexandra Trkola (ORCID: https://orcid.org/0000-0003-1013-876X)
- Michael Huber (ORCID: https://orcid.org/0000-0002-0384-0000)
- Verena Kufner (ORCID: https://orcid.org/0000-0003-4233-5952)
- Caroline V. Wiedmer
- N Müller (ORCID: https://orcid.org/0009-0005-3002-0920)
- Guido V. Bloemberg
- Elisabeth Krischer
- Tilman Obenhuber
- Ilana Reinhold
Institutions
- University of Zurich (CH)
- University Hospital of Zurich (CH)
- Institute of Virology of the Slovak Academy of Sciences (SK)
Publication Details
- Journal
- Diagnostic Microbiology and Infectious Disease
- Published
- 2025-10-09
- DOI
- https://doi.org/10.1016/j.diagmicrobio.2025.117140
- Citations
- 1
- Primary Topic
- Herpesvirus Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.35