Metabolomics integrated with network pharmacology and serum-urine pharmacochemistry unveils the antidiabetic mechanism of Anemarrhenae Rhizoma
AR ameliorates T2DM by suppressing NF-κB signalling and activating PPAR pathways, thereby improving metabolic dysregulation.
Authors
- Xiao Chang (ORCID: https://orcid.org/0000-0002-0230-0416)
- Ruolun Wang
- Yanmei Zhong (ORCID: https://orcid.org/0000-0002-2074-8038)
- Huaidong Peng (ORCID: https://orcid.org/0000-0003-1817-516X)
- Xiao Chang (ORCID: https://orcid.org/0009-0001-4671-2092)
- Jingwen Feng (ORCID: https://orcid.org/0009-0001-7427-0068)
- Xunlong Zhong
- Hairui Liang
- Xinyu Zhu (ORCID: https://orcid.org/0009-0009-1238-8878)
Institutions
- Guangdong Pharmaceutical University (CN)
- Panyu Hospital of Chinese Medicine (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.3389/fendo.2025.1618584
- Primary Topic
- Chromatography in Natural Products
- Type
- article
- Field-Weighted Citation Impact
- 0.00