Assessment of benzodiazepine dosing in status epilepticus patients in the emergency department

BZD underdosing in SE management remains widespread, with only 17% of patients receiving guideline-adherent initial doses. Although our study did not demonstrate significant differences in clinical outcomes based on dosing adequacy, implementation of institution-specific protocols and focused educational initiatives on weight-based BZD administration may improve guideline adherence in SE management.

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Publication Details

Journal
Frontiers in Neurology
Published
2025-10-09
DOI
https://doi.org/10.3389/fneur.2025.1645435
Primary Topic
Epilepsy research and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessment of benzodiazepine dosing in status epilepticus patients in the emergency department

Nora A. Kalagi, Ghadah Asaad Assiri, Raniah Aljadeed, Haya Mohammed Almalag et al.
Frontiers in Neurology
Epilepsy research and treatment
article

Assessment of benzodiazepine dosing in status epilepticus patients in the emergency department

Nora A. Kalagi, Ghadah Asaad Assiri, Raniah Aljadeed, Haya Mohammed Almalag, Rana Aljadeed, Huda Alewairdhi, Amenah Alkaf, Daad Alhajlbrahim
article en

Abstract

BZD underdosing in SE management remains widespread, with only 17% of patients receiving guideline-adherent initial doses. Although our study did not demonstrate significant differences in clinical outcomes based on dosing adequacy, implementation of institution-specific protocols and focused educational initiatives on weight-based BZD administration may improve guideline adherence in SE management.

Frontiers in NeurologyVol. 16
King Saud University (SA), Hikma Pharmaceuticals (United Kingdom) (GB)
Openalex Percentile: Top 66%
Epilepsy research and treatment
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