Blood-derived ratio indexes associated with severity and prognosis of immune checkpoint inhibitor-related cardiotoxicity: a retrospective analysis
SIRI and NLR are effectively associated with iRC severity and could stratify the risk of developing poor short- and long-term prognoses. These readily available inflammatory indexes could improve risk assessment and guide clinical decision-making for iRC patients. However, further prospective studies should validate their utility in diverse populations.
Authors
- Zhenli Li (ORCID: https://orcid.org/0000-0002-3682-164X)
- Lingfei Guo (ORCID: https://orcid.org/0000-0002-4885-625X)
- Tiezhu Yao (ORCID: https://orcid.org/0000-0002-2851-2812)
- Guangbin Gao (ORCID: https://orcid.org/0009-0009-3460-8712)
- Tianchun Wang (ORCID: https://orcid.org/0000-0003-3051-9447)
- Jing Liu (ORCID: https://orcid.org/0000-0002-3113-4015)
- Guang Liu (ORCID: https://orcid.org/0000-0003-0468-1061)
- Yansong Wang (ORCID: https://orcid.org/0000-0002-4532-9921)
- Zhengkun Guan
- Jingtao Ma
- Qian Jiao (ORCID: https://orcid.org/0009-0003-0576-8297)
Institutions
- Hebei Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Fourth Hospital of Hebei Medical University (CN)
- Guang’anmen Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.3389/fonc.2025.1676806
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00