Combined inflammatory-lipid index and tumor markers for predicting the spatial localization of lesions in early-stage non-small cell lung cancer
WBC count, lymphocyte count, α-HBDH, HDL, CEA, SF, CA153, and CA199 are significant predictors of lesion localization in early-stage NSCLC. The developed nomogram, based on readily available clinical parameters, demonstrated strong predictive performance and may aid in individualized diagnosis and treatment planning. Further large-scale external validation is needed.
Authors
- Zhaoping Cheng (ORCID: https://orcid.org/0000-0001-7217-7284)
- Hao Ren (ORCID: https://orcid.org/0000-0001-9206-7760)
- Jiankang Xu (ORCID: https://orcid.org/0009-0005-2753-2976)
- Shilei Zhao (ORCID: https://orcid.org/0000-0002-8168-8112)
- Bin Zhang (ORCID: https://orcid.org/0000-0002-6286-6227)
- Zichen Yang
- Dengfeng Ge
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-09
- DOI
- https://doi.org/10.3389/fonc.2025.1635315
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Jiangsu Province