Effects of permissive hypercapnia on intraoperative cerebral oxygenation and early postoperative cognitive function in elderly patients undergoing laparoscopic surgery
Permissive hypercapnia significantly improves rSO<sub>2</sub> and was associated with smaller early declines in MMSE scores, suggesting a potential benefit on global cognition. These findings are exploratory and should be confirmed using comprehensive neuropsychological batteries.
Authors
- Shuang Zhao (ORCID: https://orcid.org/0000-0001-7081-6177)
- Fang Zhao (ORCID: https://orcid.org/0000-0002-5485-5333)
- Guanhua Dou (ORCID: https://orcid.org/0000-0002-5669-3067)
- Jiang Huo
- Huixian Chen (ORCID: https://orcid.org/0000-0003-2808-5360)
- Qianqian Zhao (ORCID: https://orcid.org/0000-0002-5944-8710)
- Yingqun Yu
Institutions
- Chinese PLA General Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-10-09
- DOI
- https://doi.org/10.3389/fmed.2025.1575412
- Citations
- 1
- Primary Topic
- Cardiac, Anesthesia and Surgical Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.39