Medicine for artificial intelligence: applying a medical framework to AI anomalies

We propose Medicine for Artificial Intelligence (MAI), a clinical framework that reconceptualizes AI anomalies as diseases requiring systematic screening, differential diagnosis, treatment, and follow-up. Contemporary discourse on failures (e.g., "hallucination") is <i>ad hoc</i> and fragmented across domains, impeding cumulative knowledge and reproducible management. MAI adapts medical nosology to AI by formalizing core constructs-disease, symptom, diagnosis, treatment, and classification-and mapping a clinical workflow (examination → diagnosis → intervention) onto the AI lifecycle. As a proof-of-concept, we developed DSA-1, a prototype taxonomy of 45 disorders across nine functional chapters. This approach clarifies ambiguous failure modes (e.g., distinguishing hallucination subtypes), links diagnoses to actionable interventions and evaluation metrics, and supports lifecycle practices, including triage and "AI health checks." MAI further maps epidemiology, severity, and detectability to risk-assessment constructs, complementing top-down governance with bottom-up technical resolution. By aligning clinical methodology with AI engineering and coordinating researchers, clinicians, and regulators, MAI offers a reproducible foundation for safer, more resilient, and auditable AI systems.

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Publication Details

Journal
Frontiers in Artificial Intelligence
Published
2025-10-09
DOI
https://doi.org/10.3389/frai.2025.1698717
Citations
1
Primary Topic
Neuroethics, Human Enhancement, Biomedical Innovations
Type
article
Field-Weighted Citation Impact
1.43
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article

Medicine for artificial intelligence: applying a medical framework to AI anomalies

Shumpei Ishikawa, Daisuke Komura, Binay Panda, Takahiro Kato
1 citations
Frontiers in Artificial Intelligence
Neuroethics, Human Enhancement, Biomedical Innovations
1.43
article

Medicine for artificial intelligence: applying a medical framework to AI anomalies

Shumpei Ishikawa, Daisuke Komura, Binay Panda, Takahiro Kato
article en
1 citations

Abstract

We propose Medicine for Artificial Intelligence (MAI), a clinical framework that reconceptualizes AI anomalies as diseases requiring systematic screening, differential diagnosis, treatment, and follow-up. Contemporary discourse on failures (e.g., "hallucination") is <i>ad hoc</i> and fragmented across domains, impeding cumulative knowledge and reproducible management. MAI adapts medical nosology to AI by formalizing core constructs-disease, symptom, diagnosis, treatment, and classification-and mapping a clinical workflow (examination → diagnosis → intervention) onto the AI lifecycle. As a proof-of-concept, we developed DSA-1, a prototype taxonomy of 45 disorders across nine functional chapters. This approach clarifies ambiguous failure modes (e.g., distinguishing hallucination subtypes), links diagnoses to actionable interventions and evaluation metrics, and supports lifecycle practices, including triage and "AI health checks." MAI further maps epidemiology, severity, and detectability to risk-assessment constructs, complementing top-down governance with bottom-up technical resolution. By aligning clinical methodology with AI engineering and coordinating researchers, clinicians, and regulators, MAI offers a reproducible foundation for safer, more resilient, and auditable AI systems.

Frontiers in Artificial IntelligenceVol. 8
Jawaharlal Nehru University (IN), Bunkyo University (JP), The University of Tokyo (JP)
Openalex Percentile: Top 15%
Neuroethics, Human Enhancement, Biomedical Innovations
1.43
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